You can reach Brindisi Airport using some of most popular air lines companies. You can find below some examples.

London

Ryanair, Alitalia, Lufthansa, KLM, Air France, Airone

Paris

Airfrance, KLM, Airone, Alitalia, Lufthansa

Zurich

Alitalia, Swiss Air, AIr Berlin, Air France

Munchen

Alitalia, Lufthansa, SAS Scandinavian, Air Dolomiti

Wien

Alitalia, Lufthansa, Austrian Air

Praha

Alitalia, Lufthansa, Czech Air

Oslo, Stockholm, Helsinki

KLM, Alitalia, Air France
Madrid
Iberia, Alitalia, Air France, Air Eurpa
Amsterdam
Air France, KLM, Lufthansa, Alitalia, Airone
Kobenhavn
Alitalia, Air France, SAS Scandinavian, Swiss, Lufthansa, Austrian Air, Czech Air.
You can reach the city of Lecce using shuttle bus service, operating from Brindisi Airport to Lecce Terminal, then Domus Open Space provides to pick up its guests using own shuttle service.
 

San Donato di Lecce is situated at 7 km from Lecce(map), the village is well connected by an excellent road network: at the east side the ss 16 lecce-maglie at the west side with the ss 476 lecce-galatina, you can reach the city at the most in 10 minutes. Its strategic position (routes) very close to the city, makes it very easy to reach both the Ionic and Adriatic sea, in about 25/30 minutes you can reach the coasts and in about the same time also other places..for example to reach Torre dell'orso you only have about 24 km. The road network to reach the fun places of the 2 coasts, Gallipoli or Otranto is very good. In this way since you are in the centre of the Salento you can choose easily your favourite destination: cities, sea at east and sea at west!